Authors Y Mohan DasDepartment of Computer Science and Engineering (Data Science), Gates Institute of Technology, Gooty, Andhra Pradesh, IndiaPatnam Naveen KumarDepartment of Computer Science and Engineering (Data Science), Gates Institute of Technology, Gooty, Andhra Pradesh, IndiaChakali RohithaDepartment of Computer Science and Engineering (Data Science), Gates Institute of Technology, Gooty, Andhra Pradesh, IndiaElluru Bharath KumarDepartment of Computer Science and Engineering (Data Science), Gates Institute of Technology, Gooty, Andhra Pradesh, IndiaMeesala PraveenaDepartment of Computer Science and Engineering (Data Science), Gates Institute of Technology, Gooty, Andhra Pradesh, IndiaBattu SnehaDepartment of Computer Science and Engineering (Data Science), Gates Institute of Technology, Gooty, Andhra Pradesh, India Abstract Since coronavirus has shown up, inaccessibility of legitimate clinical resources is at its peak, like the shortage of specialists and healthcare workers, lack of proper equipment and medicines etc. The entire medical fraternity is in distress, which results in numerous individual’s demise. Due to unavailability, individuals started taking medication independently without appropriate consultation, making the health condition worse than usual. As of late, machine learning has been valuable in numerous applications, and there is an increase in innovative work for automation. This paper intends to present a drug recommender system that can drastically reduce specialist’s heap. In this research, we build a medicine recommendation system that uses patient reviews to predict the sentiment using various vectorization processes like Bow, TF-IDF, Word2Vec, and Manual Feature Analysis, which can help recommend the top drug for a given disease by different classification algorithms. The predicted sentiments were evaluated by precision, recall, f1score, accuracy, and AUC score. The results show that classifier Linear SVC using TF- IDF vectorization outperforms all other models with 93% accuracy. Keywords Drug Recommender System Machine Learning NLP Smote Bow TF-IDF Word2Vec Sentiment analysis Citation of this Article Y Mohan Das, Patnam Naveen Kumar, Chakali Rohitha, Elluru Bharath Kumar, Meesala Praveena, & Battu Sneha. (2025). Integrated ML with NLP Frame Work for the Drug Recommendation. Journal of Artificial Intelligence and Emerging Technologies. 2(3), 24-28. Article DOI: https://doi.org/10.47001/JAIET/2025.203005 Licence Copyright (c) 2026 Journal of Artificial Intelligence and Emerging Technologies. This work is licensed under a Creative Commons Attribution Non Commercial 4.0 International Licence. References Battineni, G.; Sagaro, G.G.; Chintalapudi, N.; Di Canio, M.; Amenta, F. Assessment of Awareness and Knowledge on Novel Coronavirus (COVID-19) Pandemic among Seafarers. Healthcare 2021, 9, 120.Goh, J.M.; Gao, G.; Agarwal, R. The creation of social value: Can an online health community reduce rural– urban health disparities? MIS Q. 2016, 40, 247–263.Cook, S.F.; Bies, R.R. Disease Progression Modeling: Key Concepts and Recent Developments. Curr. Pharmacol. Rep. 2016, 2,221–230.Koren, Y. Factorization Meets the Neighborhood: A Multifaceted Collaborative Filtering Model. In Proceedings of the 14thACM SIGKDD International Conference on Knowledge Discovery and Data Mining, Las Vegas, NV, USA, 24–27 August 2008;pp. 426– 434.Ye, Q.; Hsieh, C.Y.; Yang, Z.; Kang, Y.; Chen, J.; Cao, D.; He, S.; Hou, T. A unified drug-target interaction prediction framework based on knowledge graph and recommendation system. Nat. Commun. 2021, 12, 6775.Fox, S.; Duggan, M. Health Online 2013; Pew Research Internet Project Report: Washington, DC, USA, 2013. pp. 191–194.Subramaniyaswamy, V.; Manogaran, G.; Logesh, R.; Vijayakumar, V.; Chilamkurti, N.; Malathi, D.; Senthil selvan, N. An ontology driven personalized food recommendation in IoT-based healthcare system. J. Super comput. 2019, 75, 3184–3216.Liang, T.P. Recommender systems for decision support. Expert Syst. Appl. 2008, 45, 385–38.Chintalapudi, N.; Angeloni, U.; Battineni, G.; di Canio, M.; Marotta, C.; Rezza, G.; Sagaro, G.G.; Silenzi, A.; Amenta, F. LASSO Regression Modeling on Prediction of Medical Terms among Seafarers’ Health Documents Using Tidy Text Mining. Bioengineering2022, 9, 124.Lu, J.; Wu, D.; Mao, M.; Wang, W.; Zhang, G. Recommender system application developments: A survey. Decis. Support Syst.2015, 74, 12–32.Huang, F.; Wang, S.; Chan, C.-C. Predicting disease by using data mining based on healthcare information system. In Proceedings of the 2012 IEEE International Conference on granular.