Authors

Parvathy Gunasekaran

Department of Computer Science Engineering, Acharya Institute of Technology, Bangalore, India

Nanjundeshwaran Kannappa

Department of Computer Science Engineering, Acharya Institute of Technology, Bangalore, India

Abinav Rao

Department of Computer Science Engineering, Acharya Institute of Technology, Bangalore, India

Abstract

Osteo carcinoma (osteosarcoma) is an aggressive primary bone malignancy that requires early and accurate diagnosis to improve patient survival and treatment outcomes. Radiological imaging modalities such as X-ray and Magnetic Resonance Imaging (MRI) play a crucial role in detecting structural and soft tissue abnormalities associated with bone tumors. However, manual interpretation of these images is time-consuming and subject to variability among radiologists. This study proposes a visualization-driven computational framework that integrates advanced image processing techniques with deep learning algorithms to enhance the detection of osteo carcinoma from X-ray and MRI images. The proposed system employs preprocessing methods including noise filtering, contrast enhancement, and normalization to improve image clarity and highlight pathological features. Texture and shape-based feature extraction techniques are combined with Convolutional Neural Network (CNN)–based classification to distinguish between normal and malignant bone tissues. Furthermore, Gradient-weighted Class Activation Mapping (Grad-CAM) is incorporated to generate interpretable heatmaps that localize tumor regions, thereby increasing clinical transparency and diagnostic confidence. Experimental results demonstrate that the integration of visualization techniques with deep learning significantly improves classification accuracy, sensitivity, and specificity compared to conventional methods. MRI images showed enhanced soft tissue delineation, while X-ray images provided effective preliminary structural assessment. The proposed framework offers a cost-effective, scalable, and clinically supportive diagnostic tool for early osteo carcinoma detection. This research highlights the potential of artificial intelligence–driven visualization systems in advancing medical imaging diagnostics and improving healthcare decision-making processes.

Keywords

Osteo Carcinoma; Osteosarcoma Detection; Medical Image Analysis; X-ray Imaging; Magnetic Resonance Imaging (MRI); Image Preprocessing; Texture Feature Extraction; Convolutional Neural Network (CNN); Deep Learning; Grad-CAM Visualization; Tumor Segmentation

Citation of this Article

Parvathy Gunasekaran, Nanjundeshwaran Kannappa, & Abinav Rao. (2025). Deep Learning–Driven Visualization Framework for Osteo Carcinoma Detection in X-Ray and MRI Images. Journal of Artificial Intelligence and Emerging Technologies (JAIET). 2(1), 20-26. Article DOI: https://doi.org/10.47001/JAIET/2025.201005

Licence Copyright (c) 2026 Journal of Artificial Intelligence and Emerging Technologies. This work is licensed under a Creative Commons Attribution Non Commercial 4.0 International Licence.

References

  1. Litjens, G., et al. (2017). A survey on deep learning in medical image analysis. Medical Image Analysis, 42, 60–88.
  2. Esteva, A., et al. (2019). A guide to deep learning in healthcare. Nature Medicine, 25, 24–29.
  3. Krizhevsky, A., Sutskever, I., & Hinton, G. (2012). ImageNet classification with deep convolutional neural networks. Advances in Neural Information Processing Systems.
  4. Selvaraju, R. R., et al. (2017). Grad-CAM: Visual explanations from deep networks via gradient-based localization. IEEE International Conference on Computer Vision.
  5. Haralick, R. M., et al. (1973). Textural features for image classification. IEEE Transactions on Systems, Man, and Cybernetics.
  6. Suzuki, K. (2017). Overview of deep learning in medical imaging. Radiological Physics and Technology, 10(3), 257–273.
  7. Greenspan, H., et al. (2016). Guest editorial: Deep learning in medical imaging. IEEE Transactions on Medical Imaging, 35(5), 1153–1159.
  8. Yasaka, K., & Abe, O. (2018). Deep learning and artificial intelligence in radiology. Japanese Journal of Radiology, 36(4), 257–264.
  9. Prabhakar Avunuri, Prashanti Siramsetti. “Efficient Ways To Detect Bone Cancer Using Image Segmentation process” International Journal of Pure and Applied Mathematics, Volume 118 No. 14 2018.
  10. Sami Bourouis, Ines Chennoufi, and Kamel Hamrouni . “Multimodal Bone Cancer Detection Using Fuzzy Classification and Variational Model” CIARP 2013, Part I, LNCS 8258, pp. 174–181, 2013. Springer-Verlag Berlin Heidelberg (2013).
  11. Sonal S. Ambalkar, S. S. Thorat. “Bone Tumor Detection from MRI Images Using Machine Learning ”International Research Journal of Engineering and Technology (2018).Volume: 05.
  12. K. Sujatha, S.Jayalakshmi, Sinthia. P. “Screening and Identify the Bone Cancer/Tumor using Image Processing.” Proceeding of IEEE International Conference on Current Trends toward Converging Technologies, Coimbatore, India,(2018).
  13. Santhanalakshmi .S.T, Abinaya.R, Affina sel. T.V, Dimple. P. “Deep Learning Based Bone Tumor Detection With Real Time Datasets.” International Research Journal of Engineering and Technology (2020) Volume:07.
  14. B. M. W. Tsui, R. N. Beck, K. Doi, and C. E. Metz, “Analysis of recorded image noise in nuclear medicine,'' Phys. Med. Biol., vol. 26, no. 5, pp. 883_902, Sep. 1981.
  15. Z. Han, B.Wei, A. Mercado, S. Leung, and S. Li, “SpineGAN: Semantic segmentation of multiple spinalstructures,'' Med. Image Anal., vol. 50, pp. 23_35, Dec. 2018.